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Distinct effects on diversifying selection by two mechanisms of immunity against Streptococcus pneumoniae.

Antigenic variation to evade host immunity has long been assumed to be a driving force of diversifying selection in pathogens. Colonization by Streptococcus pneumoniae, which is central to the organism's transmission and therefore evolution, is limited by two arms of the immune system: antibody...

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Detalhes bibliográficos
Main Authors: Yuan Li, Todd Gierahn, Claudette M Thompson, Krzysztof Trzciński, Christopher B Ford, Nicholas Croucher, Paulo Gouveia, Jessica B Flechtner, Richard Malley, Marc Lipsitch
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC3493470?pdf=render
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