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A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling

STAT3 and Akt signaling have been validated as potential molecular targets for treatment of cancers including melanoma. These small molecule inhibitors of STAT3 or Akt signaling are promising for developing anti-melanoma therapeutic agents. MLS-2438, a novel 7-bromoindirubin, a derivative of the nat...

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書誌詳細
主要な著者: Liu, Lucy, Kritsanida, Marina, Magiatis, Prokopios, Gaboriaud, Nicolas, Wang, Yan, Wu, Jun, Buettner, Ralf, Yang, Fan, Nam, Sangkil, Skaltsounis, Leandros, Jove, Richard
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493432/
https://ncbi.nlm.nih.gov/pubmed/22895078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21781
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