The yeast Fun30 and human SMARCAD1 chromatin remodelers promote DNA end resection

Several homology-dependent pathways can repair potentially lethal DNA double-strand breaks (DSBs). The first step common to all homologous recombination reactions is the 5′-3′ degradation of DSB ends that yields 3′ single-stranded DNA (ssDNA) required for loading of checkpoint and recombination prot...

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Hauptverfasser: Costelloe, Thomas, Louge, Raphaël, Tomimatsu, Nozomi, Mukherjee, Bipasha, Martini, Emmanuelle, Khadaroo, Basheer, Dubois, Kenny, Wiegant, Wouter W., Thierry, Agnès, Burma, Sandeep, van Attikum, Haico, Llorente, Bertrand
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493121/
https://ncbi.nlm.nih.gov/pubmed/22960744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11353
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