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The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's disease

There are several familial forms of Alzheimer's disease (AD) most of which are caused by mutations in the genes that encode the presenilin enzymes involved in the production of amyloid-β (Aβ) from the amyloid precursor protein (APP). In AD, Aβ forms fibrils that are deposited in the brain as pl...

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Detalhes bibliográficos
Main Authors: PORTELIUS, ERIK, FORTEA, JUAN, MOLINUEVO, JOSE LUIS, GUSTAVSSON, MIKAEL K., ANDREASSON, ULF, SANCHEZ-VALLE, RAQUEL
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493058/
https://ncbi.nlm.nih.gov/pubmed/22307680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2012.774
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