Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

BACKGROUND: Alzheimer's disease (AD) is associated with deposition of amyloid β (Aβ) in the brain, which is reflected by low concentration of the Aβ1-42 peptide in the cerebrospinal fluid (CSF). There are at least 15 additional Aβ peptides in human CSF and their relative abundance pattern is th...

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Detalhes bibliográficos
Main Authors: Portelius, Erik, Andreasson, Ulf, Ringman, John M, Buerger, Katharina, Daborg, Jonny, Buchhave, Peder, Hansson, Oskar, Harmsen, Andreas, Gustavsson, Mikael K, Hanse, Eric, Galasko, Douglas, Hampel, Harald, Blennow, Kaj, Zetterberg, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818651/
https://ncbi.nlm.nih.gov/pubmed/20145736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-2
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