Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele

Misfolding and aggregation of amyloid β (Aβ) are key features of Alzheimer's disease (AD) pathogenesis, but the molecular events controlling this process are not known in detail. In vivo, Aβ aggregation and plaque formation occur in the interstitial fluid of the brain extracellular matrix. This...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Res
Prif Awduron: Padayachee, E.R., Zetterberg, H., Portelius, E., Borén, J., Molinuevo, J.L., Andreasen, N., Cukalevski, R., Linse, S., Blennow, K., Andreasson, U.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier/North-Holland Biomedical Press 2016
Pynciau:
Research Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090044/
https://ncbi.nlm.nih.gov/pubmed/27653981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.09.022
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