Targeting COX-2/PGE(2) Pathway in HIPK2 Knockdown Cancer Cells: Impact on Dendritic Cell Maturation

BACKGROUND: Homeodomain-interacting protein kinase 2 (HIPK2) is a multifunctional protein that exploits its kinase activity to modulate key molecular pathways in cancer to restrain tumor growth and induce response to therapies. For instance, HIPK2 knockdown induces upregulation of oncogenic hypoxia-...

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Detalhes bibliográficos
Main Authors: Garufi, Alessia, Pistritto, Giuseppa, Ceci, Claudia, Di Renzo, Livia, Santarelli, Roberta, Faggioni, Alberto, Cirone, Mara, D’Orazi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492329/
https://ncbi.nlm.nih.gov/pubmed/23144866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048342
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