Targeting COX-2/PGE(2) Pathway in HIPK2 Knockdown Cancer Cells: Impact on Dendritic Cell Maturation

BACKGROUND: Homeodomain-interacting protein kinase 2 (HIPK2) is a multifunctional protein that exploits its kinase activity to modulate key molecular pathways in cancer to restrain tumor growth and induce response to therapies. For instance, HIPK2 knockdown induces upregulation of oncogenic hypoxia-...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Garufi, Alessia, Pistritto, Giuseppa, Ceci, Claudia, Di Renzo, Livia, Santarelli, Roberta, Faggioni, Alberto, Cirone, Mara, D’Orazi, Gabriella
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492329/
https://ncbi.nlm.nih.gov/pubmed/23144866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048342
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