Hyperglycemia triggers HIPK2 protein degradation

Homeodomain interacting protein kinase-2 (HIPK2) is an evolutionary conserved kinase that modulates several key molecular pathways to restrain tumor growth and induce p53-depending apoptotic cell-death in response to anticancer therapies. HIPK2 silencing in cancer cells leads to chemoresistance and...

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Vydáno v:Oncotarget
Hlavní autoři: Baldari, Silvia, Garufi, Alessia, Granato, Marisa, Cuomo, Laura, Pistritto, Giuseppa, Cirone, Mara, D'Orazi, Gabriella
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352047/
https://ncbi.nlm.nih.gov/pubmed/27901482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13595
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