Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging

Small non-coding microRNAs are believed to be involved in the mechanism of aging but nothing is known on the impact of microRNAs in the progeroid disorder Werner syndrome (WS). WS is a premature aging disorder caused by mutations in a RecQ-like DNA helicase. Mice lacking the helicase domain of the W...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dallaire, Alexandra, Garand, Chantal, Paquet, Eric R., Mitchell, Sarah J., de Cabo, Rafael, Simard, Martin J., Lebel, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492227/
https://ncbi.nlm.nih.gov/pubmed/23075628
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados