RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice

Mitochondrial function declines with age in postmitotic tissues such as brain, heart and skeletal muscle. Despite weekly exercise, aged mice showed substantial losses of mtDNA gene copy numbers and reductions in mtDNA gene transcription and mitobiogenesis signaling in brain and heart. We treated the...

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Detalhes bibliográficos
Main Authors: Thomas, Ravindar R., Khan, Shaharyar M., Smigrodzki, Rafal M., Onyango, Isaac G., Dennis, Jameel, Khan, Omer M., Portell, Francisco R., Bennett, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492226/
https://ncbi.nlm.nih.gov/pubmed/23075607
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