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Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.

We have used a special class of human acute lymphocytic leukemias, the common "non-T/non-B" cell type, to define a hierarchy of genetic rearrangements that occur during the earliest stages of B-cell maturation. This has allowed us to identify intermediate cells predicted by a hierarchial m...

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Main Authors: Korsmeyer, S J, Hieter, P A, Ravetch, J V, Poplack, D G, Waldmann, T A, Leder, P
格式: Artigo
語言:Inglês
出版: 1981
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC349202/
https://ncbi.nlm.nih.gov/pubmed/6273911
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