Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.
We have used a special class of human acute lymphocytic leukemias, the common "non-T/non-B" cell type, to define a hierarchy of genetic rearrangements that occur during the earliest stages of B-cell maturation. This has allowed us to identify intermediate cells predicted by a hierarchial model in wh...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1981
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349202/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.7096 |
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