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Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.

We have used a special class of human acute lymphocytic leukemias, the common "non-T/non-B" cell type, to define a hierarchy of genetic rearrangements that occur during the earliest stages of B-cell maturation. This has allowed us to identify intermediate cells predicted by a hierarchial model in wh...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Korsmeyer, S J, Hieter, P A, Ravetch, J V, Poplack, D G, Waldmann, T A, Leder, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.7096
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