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Identification of the Ah-Receptor Structural Determinants for Ligand Preferences

The aryl hydrocarbon receptor (AHR) is a transcription factor that responds to diverse ligands and plays a critical role in toxicology, immune function, and cardiovascular physiology. The structural basis of the AHR for ligand promiscuity and preferences is critical for understanding AHR function. B...

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Detalhes bibliográficos
Main Authors: Xing, Yongna, Nukaya, Manabu, Satyshur, Kenneth A., Jiang, Li, Stanevich, Vitali, Korkmaz, Elif Nihal, Burdette, Lisa, Kennedy, Gregory D., Cui, Qiang, Bradfield, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491955/
https://ncbi.nlm.nih.gov/pubmed/22659362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs194
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