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Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis.
The contribution of proofreading to the fidelity of catalysis by DNA polymerases has been determined with deoxyribonucleoside [1-thio]triphosphate substrates. These analogues, which contain a sulfur in place of an oxygen on the alpha phosphorus, are incorporated into DNA by DNA polymerases at rates...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1981
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6458818/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.6734 |
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