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Two Structures of a Thiazolinyl Imine Reductase from Yersinia enterocolitica (Irp3) Provide Insight for Catalysis and Binding to the Nonribosomal Peptide Synthetase Module of HMWP1
The thiazolinyl imine reductase from Yersinia enterocolitica (Irp3) catalyzes the NADPH-dependent reduction of a thiazoline ring in an intermediate for the formation of the siderophore yersiniabactin. Two structures of Irp3 were determined in the apo- (1.85 Å) and NADP(+)-bound (2.31 Å) forms. Irp3...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491095/ https://ncbi.nlm.nih.gov/pubmed/23066849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3011016 |
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