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Impaired Pten Expression in Human Malignant Peripheral Nerve Sheath Tumours
Malignant peripheral nerve sheath tumours (MPNST) are aggressive sarcomas that develop in about 10% of patients with the genetic disease neurofibromatosis type 1 (NF1). Molecular alterations contributing to MPNST formation have only partially been resolved. Here we examined the role of Pten, a key r...
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Autores principales: | , , , , , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3490977/ https://ncbi.nlm.nih.gov/pubmed/23139750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047595 |
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