Impaired Pten Expression in Human Malignant Peripheral Nerve Sheath Tumours

Malignant peripheral nerve sheath tumours (MPNST) are aggressive sarcomas that develop in about 10% of patients with the genetic disease neurofibromatosis type 1 (NF1). Molecular alterations contributing to MPNST formation have only partially been resolved. Here we examined the role of Pten, a key r...

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Detalhes bibliográficos
Main Authors: Bradtmöller, Maren, Hartmann, Christian, Zietsch, Jan, Jäschke, Sebastian, Mautner, Victor-F, Kurtz, Andreas, Park, Su-Jin, Baier, Michael, Harder, Anja, Reuss, David, von Deimling, Andreas, Heppner, Frank L., Holtkamp, Nikola
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490977/
https://ncbi.nlm.nih.gov/pubmed/23139750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047595
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