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Intrinsic coupling of lagging-strand synthesis to chromatin assembly
Fifty per cent of the genome is discontinuously replicated on the lagging strand as Okazaki fragments. Eukaryotic Okazaki fragments remain poorly characterized and, because nucleosomes are rapidly deposited on nascent DNA, Okazaki fragment processing and nucleosome assembly potentially affect one an...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3490407/ https://ncbi.nlm.nih.gov/pubmed/22419157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10895 |
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