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Structure and Function of Non-Native Metal Clusters in Human Arginase I

Various binuclear metal ion clusters and complexes have been reconstituted in crystalline human arginase I by removing the Mn(2+)(2)-cluster of the wild-type enzyme with metal chelators and subsequently soaking the crystalline apoenzyme in buffer solutions containing NiCl(2) or ZnCl(2). X-ray crysta...

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Main Authors: D’Antonio, Edward L., Hai, Yang, Christianson, David W.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490219/
https://ncbi.nlm.nih.gov/pubmed/23061982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301145n
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