Llwytho...

Bim dictates naïve CD4 T cell lifespan and the development of age-associated functional defects()

With age peripheral naïve CD4 T cells become both longer-lived and functionally impaired and they express reduced levels of Bim, a pro-apoptotic Bcl-family member. In this study, we show that reduced Bim expression by naïve CD4 T cells intrinsically mediates their longer lifespan in the periphery. M...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tsukamoto, Hirotake, Huston, Gail E., Dibble, John, Duso, Debra K., Swain, Susan L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490203/
https://ncbi.nlm.nih.gov/pubmed/20844198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001668
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!