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Depletion of GGA1 and GGA3 Mediates Postinjury Elevation of BACE1

Traumatic brain injury (TBI) is one of the most robust environmental risk factors for Alzheimer's disease (AD). Compelling evidence is accumulating that a single event of TBI is associated with increased levels of Aβ. However, the underlying molecular mechanisms remain unknown. We report here t...

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Bibliografiske detaljer
Main Authors: Walker, Kendall R., Kang, Eugene L., Whalen, Michael J., Shen, Yong, Tesco, Giuseppina
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490187/
https://ncbi.nlm.nih.gov/pubmed/22836275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5491-11.2012
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