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Depletion of GGA1 and GGA3 Mediates Postinjury Elevation of BACE1

Traumatic brain injury (TBI) is one of the most robust environmental risk factors for Alzheimer's disease (AD). Compelling evidence is accumulating that a single event of TBI is associated with increased levels of Aβ. However, the underlying molecular mechanisms remain unknown. We report here t...

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Detalhes bibliográficos
Main Authors: Walker, Kendall R., Kang, Eugene L., Whalen, Michael J., Shen, Yong, Tesco, Giuseppina
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490187/
https://ncbi.nlm.nih.gov/pubmed/22836275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5491-11.2012
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