Loading...
Agonist-promoted Lys 63-linked polyubiquitination of the human kappa opioid receptor is involved in receptor down-regulation
Ubiquitination of the human κ opioid receptor (hKOR) expressed in CHO cells was observed in the presence of the proteasomal inhibitor MG132 and enhanced by the agonists U50,488H and dynorphin A (Dyn A). The dominant negative (DN) mutants GRK2-K220R and β-arrestin (319–418), but not dynamin I-K44A, r...
Na minha lista:
Main Authors: | , , |
---|---|
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2008
|
Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489932/ https://ncbi.nlm.nih.gov/pubmed/18212250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.042846 |
Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|