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TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis
The engagement of Toll-like receptor 3 (TLR3) leads to the oligomerization of the adaptor TICAM-1 (TRIF), which can induces either of three acute cellular responses, namely, cell survival coupled to Type I interferon production, or cell death, via apoptosis or necrosis. The specific response elicite...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489747/ https://ncbi.nlm.nih.gov/pubmed/23162759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21244 |
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