Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1

BACKGROUND: CADM1 encodes an immunoglobulin superfamily (IGSF) cell adhesion molecule. Inactivation of CADM1, either by promoter hypermethylation or loss of heterozygosity, has been reported in a wide variety of tumor types, thus it has been postulated as a tumor suppressor gene. FINDINGS: We show f...

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Autori principali: van der Weyden, Louise, Arends, Mark J, Rust, Alistair G, Poulogiannis, George, McIntyre, Rebecca E, Adams, David J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489691/
https://ncbi.nlm.nih.gov/pubmed/22553910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-29
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