Acute sensitivity of the oral mucosa to oncogenic K-ras

Mouse models of cancer represent powerful tools for analysing the role of genetic alterations in carcinogenesis. Using a mouse model that allows tamoxifen-inducible somatic activation (by Cre-mediated recombination) of oncogenic K-ras(G12D) in a wide range of tissues, we observed hyperplasia of squa...

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Main Authors: van der Weyden, Louise, Alcolea, Maria P, Jones, Philip H, Rust, Alistair G, Arends, Mark J, Adams, David J
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd. 2011
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Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627303/
https://ncbi.nlm.nih.gov/pubmed/21381032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2853
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