Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation

Genetic screens in simple model organisms have identified many of the key components of the conserved signal transduction pathways that are oncogenic when misregulated. Here, we identify H37N21.1 as a gene that regulates vulval induction in let-60(n1046gf), a strain with a gain-of-function mutation...

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Bibliografiska uppgifter
Huvudupphovsmän: Wilson, Catherine H, Crombie, Catriona, van der Weyden, Louise, Poulogiannis, George, Rust, Alistair G, Pardo, Mercedes, Gracia, Tannia, Yu, Lu, Choudhary, Jyoti, Poulin, Gino B, McIntyre, Rebecca E, Winton, Douglas J, March, H Nikki, Arends, Mark J, Fraser, Andrew G, Adams, David J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365428/
https://ncbi.nlm.nih.gov/pubmed/22510880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.91
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