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TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

TGF-β activated kinase 1 (TAK1) is a mediator of various cytokine signaling pathways. Germline deficiency of Tak1 causes multiple abnormalities, including dilated blood vessels at midgestation. However, the mechanisms by which TAK1 regulates vessel formation have not been elucidated. TAK1 binding pr...

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Bibliografische gegevens
Hoofdauteurs: Morioka, Sho, Inagaki, Maiko, Komatsu, Yoshihiro, Mishina, Yuji, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488895/
https://ncbi.nlm.nih.gov/pubmed/22972987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416198
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