TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

TGF-β activated kinase 1 (TAK1) is a mediator of various cytokine signaling pathways. Germline deficiency of Tak1 causes multiple abnormalities, including dilated blood vessels at midgestation. However, the mechanisms by which TAK1 regulates vessel formation have not been elucidated. TAK1 binding pr...

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Bibliografiska uppgifter
Huvudupphovsmän: Morioka, Sho, Inagaki, Maiko, Komatsu, Yoshihiro, Mishina, Yuji, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2012
Ämnen:
Vascular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488895/
https://ncbi.nlm.nih.gov/pubmed/22972987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416198
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