TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

TGF-β activated kinase 1 (TAK1) is a mediator of various cytokine signaling pathways. Germline deficiency of Tak1 causes multiple abnormalities, including dilated blood vessels at midgestation. However, the mechanisms by which TAK1 regulates vessel formation have not been elucidated. TAK1 binding pr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Morioka, Sho, Inagaki, Maiko, Komatsu, Yoshihiro, Mishina, Yuji, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2012
נושאים:
Vascular Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488895/
https://ncbi.nlm.nih.gov/pubmed/22972987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416198
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