TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

TGF-β activated kinase 1 (TAK1) is a mediator of various cytokine signaling pathways. Germline deficiency of Tak1 causes multiple abnormalities, including dilated blood vessels at midgestation. However, the mechanisms by which TAK1 regulates vessel formation have not been elucidated. TAK1 binding pr...

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Main Authors: Morioka, Sho, Inagaki, Maiko, Komatsu, Yoshihiro, Mishina, Yuji, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2012
主題:
Vascular Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488895/
https://ncbi.nlm.nih.gov/pubmed/22972987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416198
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