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Disruption of gingipain oligomerization into non-covalent cell-surface attached complexes

RgpA and Kgp gingipains are non-covalent complexes of endoprotease catalytic and hemagglutinin-adhesin domains on the surface of Porphyromonas gingivalis. A motif conserved in each domain has been suggested to function as an oligomerization motif. We tested this hypothesis by mutating motif residues...

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Detalhes bibliográficos
Main Authors: Sztukowska, Maryta, Veillard, Florian, Potempa, Barbara, Bogyo, Matthew, Enghild, Jan J., Thogersen, Ida B., Nguyen, Ky-Anh, Potempa, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488288/
https://ncbi.nlm.nih.gov/pubmed/22944696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2012-0175
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