Rho Isoform-specific Interaction with IQGAP1 Promotes Breast Cancer Cell Proliferation and Migration

We performed a proteomics screen for Rho isoform-specific binding proteins to clarify the tumor-promoting effects of RhoA and C that contrast with the tumor-suppressive effects of RhoB. We found that the IQ-motif-containing GTPase-activating protein IQGAP1 interacts directly with GTP-bound, prenylat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Casteel, Darren E., Turner, Stephanie, Schwappacher, Raphaela, Rangaswami, Hema, Su-Yuo, Jacqueline, Zhuang, Shunhui, Boss, Gerry R., Pilz, Renate B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488105/
https://ncbi.nlm.nih.gov/pubmed/22992742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377499
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados