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cGMP-dependent protein kinase Iβ regulates breast cancer cell migration and invasion via interaction with the actin/myosin-associated protein caldesmon

The two isoforms of type I cGMP-dependent protein kinase (PKGIα and PKGIβ) differ in their first ∼100 amino acids, giving each isoform unique dimerization and autoinhibitory domains. The dimerization domains form coiled-coil structures and serve as platforms for isoform-specific protein–protein inte...

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Detalhes bibliográficos
Main Authors: Schwappacher, Raphaela, Rangaswami, Hema, Su-Yuo, Jacqueline, Hassad, Aaron, Spitler, Ryan, Casteel, Darren E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647439/
https://ncbi.nlm.nih.gov/pubmed/23418348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.118190
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