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Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics
The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases, and controls a diverse set of cellular responses relevant to development and tumorigenesis. ErbB activation is a complex process involving receptor-ligand binding, receptor dimerization, phosphorylat...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3487696/ https://ncbi.nlm.nih.gov/pubmed/22952062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mb25190f |
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