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Quantifying the effects of co-expressing EGFR-HER2 on HER activation and trafficking

The human epidermal growth factor receptor (HER) system is an intricately regulated system that plays critical roles in development and tumorigenesis. Here, we apply integrated experimentation and modeling to analyze HER receptor activation in a panel of cell lines expressing endogenous levels of EG...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shankaran, Harish, Zhang, Yi, Opresko, Lee, Resat, Haluk
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864016/
https://ncbi.nlm.nih.gov/pubmed/18424261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.043
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