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Quantifying the effects of co-expressing EGFR-HER2 on HER activation and trafficking

The human epidermal growth factor receptor (HER) system is an intricately regulated system that plays critical roles in development and tumorigenesis. Here, we apply integrated experimentation and modeling to analyze HER receptor activation in a panel of cell lines expressing endogenous levels of EG...

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Main Authors: Shankaran, Harish, Zhang, Yi, Opresko, Lee, Resat, Haluk
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864016/
https://ncbi.nlm.nih.gov/pubmed/18424261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.043
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