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Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells

Human epidermal growth factor receptors (HER, also known as ErbB) drive cellular proliferation, pro-survival and stress responses by activating several downstream kinases, in particular ERK, p38, JNK (SAPK), the PI3K/AKT, as well as various transcriptional regulators such as STAT3. When co-expressed...

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Detalhes bibliográficos
Publicado no:Mol Biosyst
Main Authors: Gong, Chunhong, Zhang, Yi, Shankaran, Harish, Resat, Haluk
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540226/
https://ncbi.nlm.nih.gov/pubmed/25315124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00471j
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