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Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases, and controls a diverse set of cellular responses relevant to development and tumorigenesis. ErbB activation is a complex process involving receptor-ligand binding, receptor dimerization, phosphorylat...

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Detalhes bibliográficos
Main Authors: Shankaran, Harish, Zhang, Yi, Chrisler, William B., Ewald, Jonathan A., Wiley, H. Steven, Resat, Haluk
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487696/
https://ncbi.nlm.nih.gov/pubmed/22952062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mb25190f
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