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Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717

Barbiturate use in conjunction with alcohol can result in severe respiratory depression and overdose deaths. The mechanisms underlying the additive/synergistic actions were unresolved. Current management of ethanol-barbiturate-induced apnea is limited to ventilatory and circulatory support coupled w...

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Bibliografske podrobnosti
Main Authors: Ren, Jun, Ding, Xiuqing, Greer, John J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487499/
https://ncbi.nlm.nih.gov/pubmed/22837171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00752.2012
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