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Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717

Barbiturate use in conjunction with alcohol can result in severe respiratory depression and overdose deaths. The mechanisms underlying the additive/synergistic actions were unresolved. Current management of ethanol-barbiturate-induced apnea is limited to ventilatory and circulatory support coupled w...

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Detalhes bibliográficos
Main Authors: Ren, Jun, Ding, Xiuqing, Greer, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487499/
https://ncbi.nlm.nih.gov/pubmed/22837171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00752.2012
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