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Respiratory depression in rats induced by alcohol and barbiturate and rescue by ampakine CX717
Barbiturate use in conjunction with alcohol can result in severe respiratory depression and overdose deaths. The mechanisms underlying the additive/synergistic actions were unresolved. Current management of ethanol-barbiturate-induced apnea is limited to ventilatory and circulatory support coupled w...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3487499/ https://ncbi.nlm.nih.gov/pubmed/22837171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00752.2012 |
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