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The Pyrrolysine Translational Machinery as a Genetic-Code Expansion Tool

The discovery of pyrrolysine not only expanded the set of the known proteinogenic amino acids but also revealed unusual features of its encoding mechanism. The engagement of a canonical stop codon and a unique aminoacyl-tRNA synthetase–tRNA pair that can be used to accommodate a broad range of unnat...

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Autors principals: Fekner, Tomasz, Chan, Michael K.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487393/
https://ncbi.nlm.nih.gov/pubmed/21507706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2011.03.007
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