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Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems
Selenocysteine and pyrrolysine, known as the 21(st) and 22(nd) amino acids, are directly inserted into growing polypeptides during translation. Selenocysteine is synthesized via a tRNA-dependent pathway and decodes UGA (opal) codons. The incorporation of selenocysteine requires the concerted action...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795046/ https://ncbi.nlm.nih.gov/pubmed/19903474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.11.005 |
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