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Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems

Selenocysteine and pyrrolysine, known as the 21(st) and 22(nd) amino acids, are directly inserted into growing polypeptides during translation. Selenocysteine is synthesized via a tRNA-dependent pathway and decodes UGA (opal) codons. The incorporation of selenocysteine requires the concerted action...

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Hlavní autoři: Yuan, Jing, O’Donoghue, Patrick, Ambrogelly, Alex, Gundllapalli, Sarath, Sherrer, R. Lynn, Palioura, Sotiria, Simonović, Miljan, Söll, Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795046/
https://ncbi.nlm.nih.gov/pubmed/19903474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.11.005
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