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A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine
Pyrrolysine has entered natural genetic codes by the translation of UAG, a canonical stop codon. UAG translation as pyrrolysine requires the pylT gene product, an amber-decoding tRNA(Pyl) that is aminoacylated with pyrrolysine by the pyrrolysyl-tRNA synthetase produced from the pylS gene. The pylTS...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783357/ https://ncbi.nlm.nih.gov/pubmed/17204561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610294104 |
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