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PylSn and the Homologous N-terminal Domain of Pyrrolysyl-tRNA Synthetase Bind the tRNA That Is Essential for the Genetic Encoding of Pyrrolysine

Pyrrolysine is represented by an amber codon in genes encoding proteins such as the methylamine methyltransferases present in some Archaea and Bacteria. Pyrrolysyl-tRNA synthetase (PylRS) attaches pyrrolysine to the amber-suppressing tRNA(Pyl). Archaeal PylRS, encoded by pylS, has a catalytic C-term...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jiang, Ruisheng, Krzycki, Joseph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463324/
https://ncbi.nlm.nih.gov/pubmed/22851181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.396754
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