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Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette

Pyrrolysine (Pyl), the 22nd proteogenic amino acid, was restricted until recently to few organisms. Its translational use necessitates the presence of enzymes for synthesizing it from lysine, a dedicated amber stop codon suppressor tRNA, and a specific amino-acyl tRNA synthetase. The three genomes o...

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Bibliografiske detaljer
Main Authors: Borrel, Guillaume, Gaci, Nadia, Peyret, Pierre, O'Toole, Paul W., Gribaldo, Simonetta, Brugère, Jean-François
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941956/
https://ncbi.nlm.nih.gov/pubmed/24669202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/374146
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