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From quiescence to proliferation: Cdk oscillations drive the mammalian cell cycle

We recently proposed a detailed model describing the dynamics of the network of cyclin-dependent kinases (Cdks) driving the mammalian cell cycle (Gérard and Goldbeter, 2009). The model contains four modules, each centered around one cyclin/Cdk complex. Cyclin D/Cdk4–6 and cyclin E/Cdk2 promote progr...

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Bibliografische gegevens
Hoofdauteurs: Gérard, Claude, Goldbeter, Albert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487384/
https://ncbi.nlm.nih.gov/pubmed/23130001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00413
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