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The balance between cell cycle arrest and cell proliferation: control by the extracellular matrix and by contact inhibition

To understand the dynamics of the cell cycle, we need to characterize the balance between cell cycle arrest and cell proliferation, which is often deregulated in cancers. We address this issue by means of a detailed computational model for the network of cyclin-dependent kinases (Cdks) driving the m...

詳細記述

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書誌詳細
主要な著者: Gérard, Claude, Goldbeter, Albert
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996587/
https://ncbi.nlm.nih.gov/pubmed/24904738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2013.0075
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